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There is an established practice of using the electrical conductance of blood (PV loops) in heart ventricles to determine the instantaneous volume of the ventricle. This technique involves inserting a tetra-polar catheter into the ventricle and measuring conductance. This measured conductance is a combination of blood and muscle and various techniques are used to identify the blood conductance from the total measured conductance. Blood conductance can then be converted to volume using a linear (Baan) or a non-linear (Wei) relationship that relates conductance to volume. == Traditional conductance technology == This approach is based on the idea that the total conductance, G, of a fluid between two electrodes is a function of the fluid's conductivity (reciprocal of resistivity) and volume. In cardiology, a tetra-polar catheter is inserted into the ventricle and a constant current (I) is applied across the two outer electrodes. This generates an electrical field within the ventricle and the two inner electrodes measure a voltage generated due to the electric field. This measured voltage (V) is used to determine conductance through a modified version of Ohm's Law. Conductance (G) is the reciprocal of resistance (R) which changes the standard Ohm's equation from V=IR to V=I/G. Conductance is then related to blood volume though Baan's equation. When used in cardiology, the electric field generated is not limited to the blood (the fluid of interest) but also penetrates the heart wall, giving rise to additional conductance often called "parallel conductance" or "muscle conductance", Gm which must be removed. Various techniques have been attempted to remove the Gm contribution with varying degrees of success. The most common method is the hypertonic saline technique which involves injecting a bolus of hypertonic saline into the ventricle to alter blood conductivity without affecting the surrounding muscle. Another less commonly used technique involves evacuating the ventricle of blood and measuring muscle conductance alone with a conductance catheter. Clearly both techniques are unreliable, somewhat invasive and fail to account for the continuous variation in Gm over the cardiac cycle. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Admittance and conductance in cardiac performance」の詳細全文を読む スポンサード リンク
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